Diabetes (Type 1)

This study aims to determine the safety and feasibility of a tablet called empagliflozin to treat type 1 diabetes soon after it is diagnosed.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Liver Related Disease

Currently, there are no therapies approved for the treatment of NASH. The purpose of this study is to find out how safe and effective Obeticholic Acid may be in delaying specific medical conditions or health related issues that can occur in patients with NASH and evidence of liver fibrosis.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Alzheimer's disease

The main purpose of this study is to track the cognitive, lifestyle and psychological markers of a large group of community-based middle-aged adults (40-65 years inclusive) over five years online, in relation to genetic risk factors that are shown to increase risk of Alzheimer’s disease dementia in older adults.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Cancer

Are you: A smoker or recent former smoker? Aged from 55 to 80? In good general health?

If you answered yes to all three questions, you may be eligible to participate in an international research NHMRC funded study, conducted at The Royal Melbourne Hospital.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Diabetes (Type 1)

We are asking women who are pregnant and have Type 1 Diabetes themselves or have a family member with Type 1 Diabetes who would be a first-degree relative of the baby, i.e. the baby’s father or the baby’s older sibling, to consider participating.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Colitis and Crohn's Disease

Crohn’s disease is an inflammatory disease of the gastrointestinal tract (digestive tract). The purpose of this study is to see if filgotinib, an experimental drug, is effective and safe in treating people with moderate to severe Crohn’s disease.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Cancer - Brain

A new anti-epileptic-drug, called perampanel shows promise for being able to control and prevent seizures in patients with brain tumours. There are two separate studies in this project for patients with gliomas, a type of brain tumour.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Cancer - Breast

Denosumab is approved for use in osteoporosis. Laboratory research has identified other potential effects, including possibly slowing or stopping breast cell growth. The BRCA-D trial aims to investigate the effects of denosumab on normal breast tissue in patients with BRCA 1 or 2 mutations and to determine if the drug has potential to prevent breast cancer. Breast tissue will be obtained and evaluated before and after the denosumab injections.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4