Alzheimer's disease

The Melbourne University Academic Unit for Psychiatry of Old Age (AUPOA) is looking for volunteers to join the RAPID-plus trial, a study testing a new approach to treating mood symptoms in people with Alzheimer’s disease and their carers.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Cancer - Breast

The purpose of this study is to study the effects of Tamoxifen and/or Letrozole on breast cancer when given for a short time before surgery. The use of these drugs as a pre-surgery treatment is not experimental, as they are approved as the standard treatment for oestrogen positive breast cancer.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Cancer - Breast

The purpose of this research is to determine if the combination of ABT-199 and tamoxifen is safe in patients with metastatic breast cancer. We are trying to find the best combination of doses that should be given to patients, based on the side effects that patients might experience. We are also looking to establish the safest and most effective dose of ABT-199 for patients with this type of breast cancer.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Mental Health - Psychosis

The REDUCE study is testing whether or not reducing the dosage of antipsychotic medication of people recovering from their first episode of psychosis can lead to them having better recovery outcomes.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Diabetes (Type 2)

This research study is testing a new treatment for diabetes in overweight and obese people. The new drug treatment is called ZGN-1061.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Cancer

We are looking for patients who have Lynch Syndrome to enrol in our study comparing 3 different doses of aspirin for the prevention of cancer.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Multiple sclerosis

We are seeking to examine the effectiveness of a tailored cognitive behaviour (CBT) therapy based psychological intervention for the treatment of depression in people newly diagnosed with multiple sclerosis. CBT is a type of "talk therapy" that helps people learn new skills targeting their thinking and behaviour often used for the treatment of depression, anxiety.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Colitis and Crohn's Disease

Crohn’s Disease is a form of inflammatory bowel disease that is characterized by inflammation of the gastrointestinal tract. The main symptoms of active disease are abdominal pain, diarrhoea, fever and weight loss. Crohn's Disease is caused by a combination of environmental, immune and bacterial factors in genetically susceptible individuals. Traditionally, treatment has been aimed at reducing and controlling inflammation.

The main purpose of this research study is to investigate the effectiveness and safety of vedolizumab subcutaneous (SC) injection compared to placebo SC injection (dummy drug that does not contain the active medication and looks like the study medication) in patients with moderately to severely active Crohn’s Disease after an initial treatment period with vedolizumab intravenous infusion.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4