Colitis and Crohn's Disease

Crohn’s Disease is a form of inflammatory bowel disease that is characterized by inflammation of the gastrointestinal tract. The main symptoms of active disease are abdominal pain, diarrhoea, fever and weight loss. Crohn's Disease is caused by a combination of environmental, immune and bacterial factors in genetically susceptible individuals. Traditionally, treatment has been aimed at reducing and controlling inflammation.

The main purpose of this research study is to investigate the effectiveness and safety of vedolizumab subcutaneous (SC) injection compared to placebo SC injection (dummy drug that does not contain the active medication and looks like the study medication) in patients with moderately to severely active Crohn’s Disease after an initial treatment period with vedolizumab intravenous infusion.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Anaesthesia and Pain Management

Pain from wounds is common and often poorly treated. Analgesics (pain killers) taken by mouth, including narcotics, frequently fail to provide adequate pain relief and often result in side effects.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Anaesthesia and Pain Management

Nausea and vomiting are common complications of general anaesthesia. One of the drugs anaesthetists use to prevent nausea and vomiting is a drug called Dexamethasone. The PADDI Trial is a clinical trial to confirm that continued use of Dexamethasone for post-operative nausea prevention is safe and effective.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Healthy Volunteers

Cognition relates to an individual’s thinking, learning and memory processes, and can change over time.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Asthma

We are seeking participants to help test a new treatment for asthma. Our aim is to test how well this treatment works in participants with moderately severe asthma.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Alzheimer's disease

Research has shown a relationship between higher levels of brain iron, the presence of the Alzheimer’s protein, amyloid, and poorer memory and language skills. The purpose of this study is to test the effects of Deferiprone on your disease.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Transplant Research

We are seeking people to take part in a research study into whether vitamin B3 tablets reduce the number of new non-melanoma skin cancers and actinic (sun-induced) keratoses (sun spots) in people who have had an organ transplant, and who have also had previous skin cancers.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Dermatological Conditions

This study aims to see how effective a new blood test (using a diagnostic test called EUROIMMUN biochip) is in diagnosing and monitoring autoimmune blistering skin diseases, in comparison to the standard blood test.

Participants will be asked to donate an additional sample of blood which will be used for research into genetic susceptibility to autoimmune blistering skin disease. Only one visit is required and this usually will occur at the time of your visit at The Royal Melbourne Hospital.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4