Search results found: 1488
Publications
2018
Kurz, A. F., Lautenschlager, N. T.
In older adults who are developing Alzheimer-typical pathology but do not experience any symptoms-a condition termed " preclinical" Alzheimer's disease-the individual prognostic value of current biomarkers is low. Only a minority of those who have positive findings on biomarkers in the cerebrospinal fluid or upon brain imaging experience cognitive decline within 3-5 years.
Publications
Date of Publication: Jun 2018
Abo, S., Ritchie, D., Denehy, L., Panek-Hudson, Y., Irving, L., Granger, C. L.
The aims of this study are to investigate the feasibility of an exercise program commencing 60 days following allogeneic stem cell transplantation (alloSCT), to investigate changes in physical function and health-related quality of life (HRQoL) in patients from pre- to post-alloSCT and to explore changes in patient outcomes before and after the program.
Publications
Date of Publication: Dec 2018
Abou-Khalil, B., Auce, P., Avbersek, A., Bahlo, M., Balding, D. J., Bast, T., Baum, L., Becker, A. J., Becker, F., Berghuis, B., Berkovic, S. F., Boysen, K. E., Bradfield, J. P., Brody, L. C., Buono, R. J., Campbell, E., Cascino, G. D., Catarino, C.
The epilepsies affect around 65 million people worldwide and have a substantial missing heritability component. We report a genome-wide mega-analysis involving 15,212 individuals with epilepsy and 29,677 controls, which reveals 16 genome-wide significant loci, of which 11 are novel.
Publications
Date of Publication: Jun 2018
Abu-Akel, A., Bousman, C., Skafidas, E., Pantelis, C.
Currently, there is an intense pursuit of pathognomonic markers and diagnostic ('risk-based') classifiers of psychiatric conditions. Commonly, the epidemiological prevalence of the condition is not factored into the development of these classifiers. By not adjusting for prevalence, classifiers overestimate the potential of their clinical utility.
Publications
Date of Publication: Jan 2018
Abu-Akel, A., Testa, R. R., Jones, H. P., Ross, N., Skafidas, E., Tonge, B., Pantelis, C.
Objective: While diagnostically independent, autism and schizotypal disorders can co-occur. Their concurrent impact on outcomes and phenotypes has not been investigated. We investigated the impact of comorbid autism and schizotypal disorders in children on executive functioning and socio-pragmatic skills - core features of both disorders.
Publications
Date of Publication: Jan 2018
Abu-Bonsrah, K. D., Zhang, D., Bjorksten, A. R., Dottori, M., Newgreen, D. F.
Adrenomedullary chromaffin cells are catecholamine (CA)-producing cells originating from trunk neural crest (NC) via sympathoadrenal progenitors (SAPs).
Publications
Date of Publication: Sep 2018
Ackerman, I. N., Page, R. S., Fotis, K., Schoch, P., Broughton, N., Brennan-Olsen, S. L., Bucknill, A., Cross, E.
Introduction Persistent musculoskeletal conditions can impact profoundly on younger people's quality of life, psychological distress and capacity to work, as shown by previous research involving younger people with osteoarthritis.
Publications
Date of Publication: Jun 2018
Ackerman, I. N., Pratt, C., Gorelik, A., Liew, D.
Objective. To forecast the prevalence and direct health care costs of osteoarthritis (OA) and rheumatoid arthritis (RA) in Australia to the year 2030. Methods. An epidemiologic model of the Australian population was developed. Data on the national prevalence of OA and RA were obtained from the Australian Bureau of Statistics (ABS) 2014-2015 National Health Survey.