Search results found: 5861
Publications
Date of Publication: May 2016
Petrovski, S., Kury, S., Myers, C. T., Anyane-Yeboa, K., Cogne, B., Bialer, M., Xia, F., Hemati, P., Riviello, J., Mehaffey, M., Besnard, T., Becraft, E., Wadley, A., Politi, A. R., Colombo, S., Zhu, X.
Whole-exome sequencing of 13 individuals with developmental delay commonly accompanied by abnormal muscle tone and seizures identified de novo missense mutations enriched within a sub-region of GNB1, a gene encoding the guanine nucleotide-binding protein subunit beta-1, G beta.
Publications
Date of Publication: Jun 2016
Becker, G. J., Garigali, G., Fogazzi, G. B.
Urine microscopy is an important tool for the diagnosis and management of several conditions affecting the kidneys and urinary tract. In this review, we describe the automated instruments, based either on flow cytometry or digitized microscopy, that are currently in use in large clinical laboratories. These tools allow the examination of large numbers of samples in short periods.
Publications
Date of Publication: Mar 2016
Epstein, A., Leonard, H., Davis, E., Williams, K., Reddihough, D., Murphy, N., Whitehouse, A., Downs, J.
Rett syndrome is a neurodevelopmental disorder mainly affecting females and associated with a mutation on the MECP2 gene. There has been no systematic evaluation of the domains of quality of life (QOL) in Rett syndrome. The aims of this study were to explore QOL in school-aged children with Rett syndrome and compare domains with those identified in other available QOL scales.
Publications
Date of Publication: Jan 2016
Lin, M., Todaro, M., Chan, J., Churilov, L., Zhu, W. S., Ramdave, S., Mitchell, P. J., Dowling, R. J., Kwan, P., Yan, B.
BACKGROUND AND PURPOSE: Differing responses to clopidogrel following endovascular treatment of cerebrovascular diseases may increase the risk of vascular complications. CYP2C19 gene polymorphisms influence clopidogrel activity. We aimed to study the clinical impact of CYP2C19 gene polymorphisms in patients undergoing endovascular treatment.
Publications
Date of Publication: May 2016
Winton-Brown, T. T., Ting, A., Mocellin, R., Velakoulis, D., Gaillard, F.
Visual hallucinations are relatively uncommon presentations in medical and psychiatric clinics, where they are generally regarded as a marker of possible underlying "organic" brain disease. Thus, patients with visual hallucinations are often referred for imaging of the brain. This article presents a pragmatic approach for the radiologist reviewing such imaging.
Publications
Date of Publication: Jan 2016
Goldberg, G. L., Cornish, A. L., Murphy, J., Pang, E. S., Lim, L. L., Campbell, I. K., Scalzo-Inguanti, K., Chen, X. T., McMenamin, P. G., Maraskovsky, E., McKenzie, B. S., Wicks, I. P.
Granulocyte colony-stimulating factor (G-CSF) is a regulator of neutrophil production, function, and survival. Herein, we investigated the role of G-CSF in a murine model of human uveitis experimental autoimmune uveoretinitis. Experimental autoimmune uveoretinitis was dramatically reduced in G-CSF deficient mice and in anti-G-CSF monoclonal antibody treated, wild-type (WT) mice.
Publications
Date of Publication: Apr 2016
Milne, M. E., Steward, C., Firestone, S. M., Long, S. N., O',Brien, T. J., Moffat, B. A.
OBJECTIVE To develop representative MRI atlases of the canine brain and to evaluate 3 methods of atlas-based segmentation (ABS). ANIMALS 62 dogs without clinical signs of epilepsy and without MRI evidence of structural brain disease.
Publications
Date of Publication: Jan 2016
Bowyer, A. J., Royse, C. F.
Recovery is an abstract quantity the definition of which varies according to the pre-dilection of individual institutions, clinicians or patients.
Publications
Date of Publication: Jan 2016
Goh, R., Darvall, J., Wynne, R., Tatoulis, J.
The objective of this study was to investigate the prevalence of obesity and its relationship with adverse outcomes in ICU cardiothoracic patients. We performed a retrospective analysis of cardiothoracic patients admitted to The Royal Melbourne Hospital ICU between 2002 and 2014.
Publications
Date of Publication: May 2016
Soeding, P. F., Currigan, D. A., Mamo, Y., Hoy, G.
Interscalene blockade (ISB) is commonly associated with Horner's syndrome, indicating spread of injectate to the cervical sympathetic chain. Cervical sympathetic nerve activity (SNA) is believed to influence cerebral autoregulation, and a deCrease in sympathetic tone may alter cerebral blood flow (CBF). This study investigated whether ISB influenced CBF in patients undergoing shoulder surgery.