Our medical, nursing and allied health clinicians are increasingly involved in research to improve the care of our patients. This is reflected in the breadth of our research publications.
A theory-informed systematic review of clinicians' genetic testing practices
Paul, JL; Leslie, H; Trainer, AH; Gaff, C
(2018), Eur. J. Hum. Genet., 1401-1416
Identification of nine new susceptibility loci for endometrial cancer
O'Mara, TA; Glubb, DM; Amant, F; Annibali, D; Ashton, K; Attia, J; Auer, PL; Beckmann, MW; Black, A; Bolla, MK; Brauch, H; Brenner, H; Brinton, L; Buchanan, DD; Burwinkel, B; Chang-Claude, J; Chanock, SJ; Chen, C; Chen, MM; Cheng, THT; Clarke, CL; Clendenning, M; Cook, LS; Couch, FJ; Cox, A; Crous-Bous, M; Czene, K; Day, F; Dennis, J; Depreeuw, J; Doherty, JA; Dork, T; Dowdy, SC; Durst, M; Ekici, AB; Fasching, PA; Fridley, BL; Friedenreich, CM; Fritschi, L; Fung, J; Garcia-Closas, M; Gaudet, MM; Giles, GG; Goode, EL; Gorman, M; Haiman, CA; Hall, P; Hankison, SE; Healey, CS; Hein, A; Hillemanns, P; Hodgson, S; Hoivik, EA; Holliday, EG; Hopper, JL; Hunter, DJ; Jones, A; Krakstad, C; Kristensen, VN; Lambrechts, D; Le Marchand, L; Liang, XL; Lindblom, A; Lissowska, J; Long, JR; Lu, LG; Magliocco, AM; Martin, L; McEvoy, M; Meindl, A; Michailidou, K; Milne, RL; Mints, M; Montgomery, GW; Nassir, R; Olsson, H; Orlow, I; Otton, G; Palles, C; Perry, JRB; Peto, J; Pooler, L; Prescott, J; Proietto, T; Rebbeck, TR; Risch, HA; Rogers, PAW; Rubner, M; Runnebaum, I; Sacerdote, C; Sarto, GE; Schumacher, F; Scott, RJ; Setiawan, VW; Shah, M; Sheng, X; Shu, XO; Southey, MC; Swerdlow, AJ; Tham, E; Trovik, J; Turman, C; Tyrer, JP; Vachon, C; Vanden Berg, D; Vanderstichele, A; Wang, ZM; Webb, PM; Wentzensen, N; Werner, HMJ; Winham, SJ; Wolk, A; Xia, L; Xiang, YB; Yang, HP; Yu, H; Zheng, W; Pharoah, PDP; Dunning, AM; Kraft, P; De Vivo, I; Tomlinson, I; Easton, DF; Spurdle, AB; Thompson, DJ
(2018), Nat. Commun.
Is RNASEL:p.Glu265*a modifier of early-onset breast cancer risk for carriers of high-risk mutations?
Nguyen-Dumont, T; Teo, ZL; Hammet, F; Roberge, A; Mahmoodi, M; Tsimiklis, H; Park, DJ; Pope, BJ; Lonie, A; Kapuscinski, MK; Mahmood, K; Goldgar, DE; Giles, GG; Winship, I; Hopper, JL; Southey, MC
(2018), BMC Cancer
Mendelian randomisation study of age at menarche and age at menopause and the risk of colorectal cancer
Neumeyer, S; Banbury, BL; Arndt, V; Berndt, SI; Bezieau, S; Bien, SA; Buchanan, DD; Butterbach, K; Caan, BJ; Campbell, PT; Casey, G; Chan, AT; Chanock, SJ; Dai, JY; Gallinger, S; Giovannucci, EL; Giles, GG; Grady, WM; Hampe, J; Hoffmeister, M; Hopper, JL; Hsu, L; Jenkins, MA; Joshi, A; Larsson, SC; Le Marchand, L; Lindblom, A; Moreno, V; Lemire, M; Li, L; Lin, Y; Offit, K; Newcomb, PA; Pharaoh, PD; Potter, JD; Qi, LH; Rennert, G; Schafmayer, C; Schoen, RE; Slattery, ML; Song, MY; Ulrich, CM; Win, AK; White, E; Wolk, A; Woods, MO; Wu, AH; Gruber, SB; Brenner, H; Peters, U; Chang-Claude, J
(2018), Br. J. Cancer, 1639-1647
Targeting DNA repair: the genome as a potential biomarker
Nesic, K; Wakefield, M; Kondrashova, O; Scott, CL; McNeish, IA
(2018), J. Pathol., 586-597
DOI: 10.1002/path.5025
Endometrial cancer risk and survival by tumor MMR status
Nagle, CM; O'Mara, TA; Tan, Y; Buchanan, DD; Obermair, A; Blomfield, P; Quinn, MA; Webb, PM; Spurdle, AB
(2018), J. Gynecol. Oncol.
Subacute Rehabilitation Does Have Benefits for Patients With Advanced Cancer
Morgan, DD; Marston, C; Garner, J; Currow, DC
(2018), J. Pain Symptom Manage., E1-E2
Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition
Mikropoulos, C; Selkirk, CGH; Saya, S; Bancroft, E; Vertosick, E; Dadaev, T; Brendler, C; Page, E; Dias, A; Evans, DG; Rothwell, J; Maehle, L; Axcrona, K; Richardson, K; Eccles, D; Jensen, T; Osther, PJ; van Asperen, CJ; Vasen, H; Kiemeney, LA; Ringelberg, J; Cybulski, C; Wokolorczyk, D; Hart, R; Glover, W; Lam, J; Taylor, L; Salinas, M; Feliubadalo, L; Oldenburg, R; Cremers, R; Verhaegh, G; van Zelst-Stams, WA; Oosterwijk, JC; Cook, J; Rosario, DJ; Buys, SS; Conner, T; Domchek, S; Powers, J; Ausems, MGEM; Teixeira, MR; Maia, S; Izatt, L; Schmutzler, R; Rhiem, K; Foulkes, WD; Boshari, T; Davidson, R; Ruijs, M; Helderman-van den Enden, ATJM; Andrews, L; Walker, L; Snape, K; Henderson, A; Jobson, I; Lindeman, GJ; Liljegren, A; Harris, M; Adank, MA; Kirk, J; Taylor, A; Susman, R; Chen-Shtoyerman, R; Pachter, N; Spigelman, A; Side, L; Zgajnar, J; Mora, J; Brewer, C; Gadea, N; Brady, AF; Gallagher, D; van Os, T; Donaldson, A; Stefansdottir, V; Barwell, J; James, PA; Murphy, D; Friedman, E; Nicolai, N; Greenhalgh, L; Obeid, E; Murthy, V; Copakova, L; McGrath, J; Teo, SH; Strom, S; Kast, K; Leongamornlert, DA; Chamberlain, A; Pope, J; Newlin, AC; Aaronson, N; Ardern-Jones, A; Bangma, C; Castro, E; Dearnaley, D; Eyfjord, J; Falconer, A; Foster, CS; Gronberg, H; Hamdy, FC; Johannsson, O; Khoo, V; Lubinski, J; Grindedal, EM; McKinley, J; Shackleton, K; Mitra, AV; Moynihan, C; Rennert, G; Suri, M; Tricker, K; Moss, S; Kote-Jarai, Z; Vickers, A; Lilja, H; Helfand, BT; Eeles, RA
(2018), Br. J. Cancer, 266-276
DOI: 10.1038/bjc.2017.429
Canonical PRC2 function is essential for mammary gland development and affects chromatin compaction in mammary organoids
Michalak, EM; Milevskiy, MJG; Joyce, RM; Dekkers, JF; Jamieson, PR; Pal, B; Dawson, CA; Hu, YF; Orkin, SH; Alexander, WS; Lindeman, GJ; Smyth, GK; Visvader, JE
(2018), PLoS. Biol.
Current mismatch repair deficiency tumor testing practices and capabilities: A survey of Australian pathology providers
Mascarenhas, L; Shanley, S; Mitchell, G; Spurdle, AB; Macrae, F; Pachter, N; Buchanan, DD; Ward, RL; Fox, S; Duxbury, E; Driessen, R; Boussioutas, A
(2018), Asia-Pac. J. Clin. Oncol., 417-425
DOI: 10.1111/ajco.13076
Evaluating the breast cancer predisposition role of rare variants in genes associated with low-penetrance breast cancer risk SNPs
Li, N; Rowley, SM; Thompson, ER; McInerny, S; Devereux, L; Amarasinghe, KC; Zethoven, M; Lupat, R; Goode, D; Li, J; Trainer, AH; Gorringe, KL; James, PA; Campbell, IG
(2018), Breast Cancer Res.
Mutations in RECQL are not associated with breast cancer risk in an Australian population
Li, N; Rowley, SM; Goode, DL; Amarasinghe, KC; McInerny, S; Devereux, L; Wong-Brown, MW; Lupat, R; Lee, JEA; Hughes, S; Thompson, ER; Zethoven, M; Li, J; Trainer, AH; Gorringe, KL; Scott, RJ; James, PA; Campbell, IG
(2018), Nature Genet., 1346-1348
Molecular analysis of PALB2-associated breast cancers
Lee, JEA; Li, N; Rowley, SM; Cheasley, D; Zethoven, M; McInerny, S; Gorringe, KL; James, PA; Campbell, IG
(2018), J. Pathol., 53-60
DOI: 10.1002/path.5055
Ethics, health policy, and Zika: From emergency to global epidemic?
Jamrozik, E; Selgelid, MJ
(2018), J. Med. Ethics, 343-348
Maximizing the Clinical Benefit of DPYD Genotyping: Extending the Opportunity of Personalized Management to Family Members Through Cascade Testing
Higgs, EJ; Phillips, KA; Lo, LL; Winship, IM
(2018), JCO Precis. Oncol., 1-5
DOI: 10.1200/PO.18.00093
Interobserver agreement and diagnostic performance of individual MRI criteria for diagnosis of placental adhesion disorders
Goergen, SK; Posma, E; Wrede, D; Collett, J; Pyman, J; Alibrahim, E; Keene, J; Dobrotwir, A
(2018), Clin. Radiol.
Novel associations between blood DNA methylation and body mass index in middle-aged and older adults
Geurts, YM; Dugue, PA; Joo, JE; Makalic, E; Jung, CH; Guan, W; Nguyen, S; Grove, ML; Wong, EM; Hodge, AM; Bassett, JK; FitzGerald, LM; Tsimiklis, H; Baglietto, L; Severi, G; Schmidt, DF; Buchanan, DD; MacInnis, RJ; Hopper, JL; Pankow, JS; Demerath, EW; Southey, MC; Giles, GG; English, DR; Milne, RL
(2018), Int. J. Obes., 887-896
DOI: 10.1038/ijo.2017.269
Foxp1 Is Indispensable for Ductal Morphogenesis and Controls the Exit of Mammary Stem Cells from Quiescence
Fu, NY; Pal, B; Chen, YS; Jackling, FC; Milevskiy, M; Vaillant, F; Capaldo, BD; Guo, FS; Liu, KH; Rios, AC; Lim, N; Kueh, AJ; Virshup, DM; Herold, MJ; Tucker, HO; Smyth, GK; Lindeman, GJ; Visvader, JE
(2018), Dev. Cell, 629-+
Practical considerations for clinicians for transitioning patients on maintenance therapy with olaparib capsules to the tablet formulation of olaparib
Friedlander, M; Shannon, C; Goh, J; Scott, C; Mileshkin, L
(2018), Asia-Pac. J. Clin. Oncol., 459-464
DOI: 10.1111/ajco.13104
Long-term efficacy, tolerability and overall survival in patients with platinum-sensitive, recurrent high-grade serous ovarian cancer treated with maintenance olaparib capsules following response to chemotherapy
Friedlander, M; Matulonis, U; Gourley, C; du Bois, A; Vergote, I; Rustin, G; Scott, C; Meier, W; Shapira-Frommer, R; Safra, T; Matei, D; Shirinkin, V; Selle, F; Fielding, A; Lowe, ES; McMurtry, EL; Spencer, S; Rowe, P; Mann, H; Parry, D; Ledermann, J
(2018), Br. J. Cancer, 1075-1085
Improved, ACMG-compliant, in silico prediction of pathogenicity for missense substitutions encoded by TP53 variants
Fortuno, C; James, PA; Young, EL; Feng, B; Olivier, M; Pesaran, T; Tavtigian, SV; Spurdle, AB
(2018), Hum. Mutat., 1061-1069
DOI: 10.1002/humu.23553
Current review of TP53 pathogenic germline variants in breast cancer patients outside Li-Fraumeni syndrome
Fortuno, C; James, PA; Spurdle, AB
(2018), Hum. Mutat., 1764-1773
DOI: 10.1002/humu.23656
RNF43 is mutated less frequently in Lynch Syndrome compared with sporadic microsatellite unstable colorectal cancers
Fennell, LJ; Clendenning, M; McKeone, DM; Jamieson, SH; Balachandran, S; Borowsky, J; Liu, J; Kawamata, F; Bond, CE; Rosty, C; Burge, ME; Buchanan, DD; Leggett, BA; Whitehall, VLJ
(2018), Fam. Cancer, 63-69
DNA methylation-based biological aging and cancer risk and survival: Pooled analysis of seven prospective studies
Dugue, PA; Bassett, JK; Joo, JE; Jung, CH; Wong, EM; Moreno-Betancur, M; Schmidt, D; Makalic, E; Li, S; Severi, G; Hodge, AM; Buchanan, DD; English, DR; Hopper, JL; Southey, MC; Giles, GG; Milne, RL
(2018), Int. J. Cancer, 1611-1619
DOI: 10.1002/ijc.31189
Utility of immunohistochemistry for mismatch repair proteins on colorectal polyps in the familial cancer clinic
Dow, E; Buchanan, DD; Winship, IM
(2018), Intern. Med. J., 1325-1330
DOI: 10.1111/imj.13953
Physical activity and the risk of colorectal cancer in Lynch syndrome
Dashti, SG; Win, AK; Hardikar, SS; Glombicki, SE; Mallenahalli, S; Thirumurthi, S; Peterson, SK; You, YN; Buchanan, DD; Figueiredo, JC; Campbell, PT; Gallinger, S; Newcomb, PA; Potter, JD; Lindor, NM; Le Marchand, L; Haile, RW; Hopper, JL; Jenkins, MA; Basen-Engquist, KM; Lynch, PM; Pande, M
(2018), Int. J. Cancer, 2250-2260
DOI: 10.1002/ijc.31611
Somatic mutations of the coding microsatellites within the beta-2-microglobulin gene in mismatch repair-deficient colorectal cancers and adenomas
Clendenning, M; Huang, A; Jayasekara, H; Lorans, M; Preston, S; O'Callaghan, N; Pope, BJ; Macrae, FA; Winship, IM; Milne, RL; Giles, GG; English, DR; Hopper, JL; Win, AK; Jenkins, MA; Southey, MC; Rosty, C; Buchanan, DD
(2018), Fam. Cancer, 91-100
Dietary intake of one-carbon metabolism nutrients and DNA methylation in peripheral blood
Chamberlain, JA; Dugue, PA; Bassett, JK; Hodge, AM; Brinkman, MT; Joo, JE; Jung, CH; Makalic, E; Schmidt, DF; Hopper, JL; Buchanan, DD; English, DR; Southey, MC; Giles, GG; Milne, RL
(2018), Am. J. Clin. Nutr., 611-621
DOI: 10.1093/ajcn/nqy119
Genetic Counseling in the Era of Genomics: What's all the Fuss about?
Brett, GR; Wilkins, EJ; Creed, ET; West, K; Jarmolowicz, A; Valente, GM; Prawer, Y; Lynch, E; Macciocca, I
(2018), J. Genet. Couns., 1010-1021
Identification of expression quantitative trait loci associated with schizophrenia and affective disorders in normal brain tissue
Bhalala, OG; Nath, AP; Inouye, M; Sibley, CR
(2018), PLoS Genet.