Epilepsy

This study is testing a new treatment for generalised epilepsy with uncontrolled primary generalised tonic-clonic (PGTC) seizures - sometimes also referred to as Grand-Mal seizures. The new treatment is called Lacosamide. This is a double-blind, randomized, placebo-controlled, parallel-group, multicentre study.

Trial phase 

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Observational
Phase 1
Phase 2
Phase 3
Phase 4
Alzheimer's disease

Although the cause of Alzheimer’s disease is not yet clearly understood, it is believed that proteins in the brain, called beta-amyloid, are responsible. LY3202626 blocks a protein in the body called BACE1 that is responsible for the build-up of beta-amyloid. This study will look at whether the action of LY3202626 slows the progression of Alzheimer’s disease.

Trial phase 

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Observational
Phase 1
Phase 2
Phase 3
Phase 4
Fabry disease

Researchers at The Royal Melbourne Hospital are investigating several new treatments to specifically treat Fabry disease, as well as additional studies to document and monitor the manifestations of disease beyond basic medical care.

Trial phase 

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Observational
Phase 1
Phase 2
Phase 3
Phase 4
Pemphigus vulgaris

We are currently running a study of an oral mediction for people with mild to moderate pemphigus vulgaris. It is a 12-week, open label study which means that all participants in the study will be given the trial drug with a further 12 weeks of follow up.

Trial phase 

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Observational
Phase 1
Phase 2
Phase 3
Phase 4
Colitis and Crohn's Disease

The purpose of this study is to determine whether etrolizumab is a safe and effective treatment in patients with moderate to severe active ulcerative colitis that have previously had an unsuccessful response to treatment with immunosuppressants (aka TNF inhibitors - medications that reduces the activation or efficacy of the immune system) such as azathioprine, 6-mercaptopurine, or methotrexate and/or corticosteroids and to see whether etrolizumab is more effective than adalimumab in treating ulcerative colitis.

Trial phase 

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Observational
Phase 1
Phase 2
Phase 3
Phase 4
Diabetes (Type 2)

The purpose of the FIGARO-DKD clinical research study is to evaluate whether adding an investigational medication called finerenone to regular treatment is safe and effective to help reduce cardiovascular complications like heart disease or stroke in patients with type 2 diabetes and diabetic kidney disease.

Trial phase 

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Observational
Phase 1
Phase 2
Phase 3
Phase 4
Colitis and Crohn's Disease

The purpose of this study is to determine whether etrolizumab is a safe and effective treatment for ulcerative colitis in patients with moderately to severely active ulcerative colitis who have previously been treated with a class of drugs called tumour necrosis factor (TNF) inhibitors, which affects the inflammatory response of your body, but unsuccessfully.

Trial phase 

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Observational
Phase 1
Phase 2
Phase 3
Phase 4
Multiple sclerosis

The purpose of this study is to assess the effectiveness and safety of commonly used doses of Botulinum toxin (Botox) on arm shaking (or tremor) in people with multiple sclerosis (MS).

Trial phase 

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Observational
Phase 1
Phase 2
Phase 3
Phase 4