Cancer - Brain

A new anti-epileptic-drug, called perampanel shows promise for being able to control and prevent seizures in patients with brain tumours. There are two separate studies in this project for patients with gliomas, a type of brain tumour. 

Trial phase 

check
Observational
Phase 1
Phase 2
Phase 3
Phase 4
Dementia

The University of Melbourne Academic Unit for Psychiatry of Old Age (AUPOA) is looking for individuals aged 50 to 64 years who have access to the Internet and are willing to have two MRI brain scans to participate in our innovative new study of dementia risk. This study will use new, cutting edge magnetic resonance imaging technology called “7T MRI” to closely examine dementia risk factors in the brain. 

Trial phase 

check
Observational
Phase 1
Phase 2
Phase 3
Phase 4
Epilepsy

This study is testing a new treatment for generalised epilepsy with uncontrolled primary generalised tonic-clonic (PGTC) seizures - sometimes also referred to as Grand-Mal seizures. The new treatment is called Lacosamide. This is a double-blind, randomized, placebo-controlled, parallel-group, multicentre study.

Trial phase 

check
Observational
Phase 1
Phase 2
Phase 3
Phase 4
Fabry disease

Researchers at The Royal Melbourne Hospital are investigating several new treatments to specifically treat Fabry disease, as well as additional studies to document and monitor the manifestations of disease beyond basic medical care.

Trial phase 

check
Observational
Phase 1
Phase 2
Phase 3
Phase 4
Pemphigus vulgaris

We are currently running a study of an oral mediction for people with mild to moderate pemphigus vulgaris. It is a 12-week, open label study which means that all participants in the study will be given the trial drug with a further 12 weeks of follow up.

Trial phase 

check
Observational
Phase 1
Phase 2
Phase 3
Phase 4
Colitis and Crohn's Disease

The purpose of this study is to determine whether etrolizumab is a safe and effective treatment in patients with moderate to severe active ulcerative colitis that have previously had an unsuccessful response to treatment with immunosuppressants (aka TNF inhibitors - medications that reduces the activation or efficacy of the immune system) such as azathioprine, 6-mercaptopurine, or methotrexate and/or corticosteroids and to see whether etrolizumab is more effective than adalimumab in treating ulcerative colitis. Adalimumab is approved by the Therapeutic Goods Administration in Australia for

Trial phase 

check
Observational
Phase 1
Phase 2
Phase 3
Phase 4
Liver Related Disease

Currently, there are no therapies approved for the treatment of NASH. The purpose of this study is to find out how safe and effective Obeticholic Acid may be in delaying specific medical conditions or health related issues that can occur in patients with NASH and evidence of liver fibrosis. 

Trial phase 

check
Observational
Phase 1
Phase 2
Phase 3
Phase 4
Nocturia

Nocturia, defined as waking from sleep at night to urinate, is a common symptom that can have a significant impact on your health, wellbeing and lifespan. The severity of nocturia is assessed by the number of night-time toilet visits and the amount of urine passed. This is not necessarily what is of most concern to our patients.

The purpose of this project is to increase awareness about aspects of nocturia that create the most bother in day-to-day life. The information you provide will assist us, as clinicians, to better understand and address the impact of nocturia for each individual.

Trial phase 

check
Observational
Phase 1
Phase 2
Phase 3
Phase 4