Alzheimer's disease

Although the cause of Alzheimer’s disease is not yet clearly understood, it is believed that proteins in the brain, called beta-amyloid, are responsible. LY3202626 blocks a protein in the body called BACE1 that is responsible for the build-up of beta-amyloid. This study will look at whether the action of LY3202626 slows the progression of Alzheimer’s disease.

Trial phase 

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Observational
Phase 1
Phase 2
Phase 3
Phase 4
Fabry disease

Researchers at The Royal Melbourne Hospital are investigating several new treatments to specifically treat Fabry disease, as well as additional studies to document and monitor the manifestations of disease beyond basic medical care.

Trial phase 

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Observational
Phase 1
Phase 2
Phase 3
Phase 4
Dermatological Conditions

We are currently running a study of an oral mediction for people with mild to moderate pemphigus vulgaris. It is a 12-week, open label study which means that all participants in the study will be given the trial drug with a further 12 weeks of follow up.

Trial phase 

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Observational
Phase 1
Phase 2
Phase 3
Phase 4
Colitis and Crohn's Disease

The purpose of this study is to determine whether etrolizumab is a safe and effective treatment in patients with moderate to severe active ulcerative colitis that have previously had an unsuccessful response to treatment with immunosuppressants (aka TNF inhibitors - medications that reduces the activation or efficacy of the immune system) such as azathioprine, 6-mercaptopurine, or methotrexate and/or corticosteroids and to see whether etrolizumab is more effective than adalimumab in treating ulcerative colitis.

Trial phase 

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Observational
Phase 1
Phase 2
Phase 3
Phase 4
Diabetes (Type 2)

The purpose of the FIGARO-DKD clinical research study is to evaluate whether adding an investigational medication called finerenone to regular treatment is safe and effective to help reduce cardiovascular complications like heart disease or stroke in patients with type 2 diabetes and diabetic kidney disease.

Trial phase 

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Observational
Phase 1
Phase 2
Phase 3
Phase 4
Multiple sclerosis

The purpose of this study is to assess the effectiveness and safety of commonly used doses of Botulinum toxin (Botox) on arm shaking (or tremor) in people with multiple sclerosis (MS).

Trial phase 

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Observational
Phase 1
Phase 2
Phase 3
Phase 4
Diabetes (Type 1)

This study aims to determine the safety and feasibility of a tablet called empagliflozin to treat type 1 diabetes soon after it is diagnosed.

Trial phase 

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Observational
Phase 1
Phase 2
Phase 3
Phase 4
Liver Related Disease

Currently, there are no therapies approved for the treatment of NASH. The purpose of this study is to find out how safe and effective Obeticholic Acid may be in delaying specific medical conditions or health related issues that can occur in patients with NASH and evidence of liver fibrosis.

Trial phase 

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Observational
Phase 1
Phase 2
Phase 3
Phase 4