Epilepsy

This study is testing a new treatment for generalised epilepsy with uncontrolled primary generalised tonic-clonic (PGTC) seizures - sometimes also referred to as Grand-Mal seizures. The new treatment is called Lacosamide. This is a double-blind, randomized, placebo-controlled, parallel-group, multicentre study.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Fabry disease

Researchers at The Royal Melbourne Hospital are investigating several new treatments to specifically treat Fabry disease, as well as additional studies to document and monitor the manifestations of disease beyond basic medical care.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Dermatological Conditions

We are currently running a study of an oral mediction for people with mild to moderate pemphigus vulgaris. It is a 12-week, open label study which means that all participants in the study will be given the trial drug with a further 12 weeks of follow up.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Colitis and Crohn's Disease

The purpose of this study is to determine whether etrolizumab is a safe and effective treatment in patients with moderate to severe active ulcerative colitis that have previously had an unsuccessful response to treatment with immunosuppressants (aka TNF inhibitors - medications that reduces the activation or efficacy of the immune system) such as azathioprine, 6-mercaptopurine, or methotrexate and/or corticosteroids and to see whether etrolizumab is more effective than adalimumab in treating ulcerative colitis.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Colitis and Crohn's Disease

The purpose of this study is to determine whether etrolizumab is a safe and effective treatment for ulcerative colitis in patients with moderately to severely active ulcerative colitis who have previously been treated with a class of drugs called tumour necrosis factor (TNF) inhibitors, which affects the inflammatory response of your body, but unsuccessfully.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Diabetes (Type 1)

This study aims to determine the safety and feasibility of a tablet called empagliflozin to treat type 1 diabetes soon after it is diagnosed.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Alzheimer's disease

The main purpose of this study is to track the cognitive, lifestyle and psychological markers of a large group of community-based middle-aged adults (40-65 years inclusive) over five years online, in relation to genetic risk factors that are shown to increase risk of Alzheimer’s disease dementia in older adults.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4
Cancer

Are you: A smoker or recent former smoker? Aged from 55 to 80? In good general health?

If you answered yes to all three questions, you may be eligible to participate in an international research NHMRC funded study, conducted at The Royal Melbourne Hospital.

Trial phase 

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Non-Drug
Phase 1
Phase 2
Phase 3
Phase 4