Clinical trials are a very important part of the research process. New treatments, medications and medical devices cannot be approved for use in Australia without going through clinical trials. Find out more about clinical trials.
Mirikizumab for moderate to severely active Crohn’s disease
A clinical trial to assess the safety and effectiveness of a new drug, mirikizumab, for moderate to severely active Crohn’s disease.
Mirikizumabin for moderately to severely active ulcerative colitis
A clinical trial to assess the safety and effectiveness of a new drug, mirikizumab, in conventional-failed and biologic-failed patients with moderately to severely active ulcerative colitis (UC).
mRNA vaccine for preventing cytomegalovirus infection
A clinical trial seeking to develop an mRNA vaccine for preventing cytomegalovirus (CMV) infection.
Nemolizumab for the treatment of moderate to severe atopic dermatitis
A clinical trial to assess safety and effectiveness of a new drug for eczema called nemolizumab.
New add-on therapy to infliximab for ulcerative colitis
A clinical trial to assess the effectiveness of a new add-on therapy (PF-06687234) to infliximab.
New blood test to detect bowel cancer
Seeking adults diagnosed with bowel cancer who will be having surgery, chemotherapy or radiation therapy in the next 30 days for a study to assess the effectiveness of a new blood test to detect bowel cancer.
New blood test to diagnose and monitor autoimmune blistering skin conditions
A prospective study on serum antibodies against target antigens of bullous autoimmune diseases and genetic susceptibility.
New drug for basal cell carcinoma
A study to assess the safety and efficacy of ASN-002 combined with a hedgehog pathway inhibitor (vismodegib) in the treatment of multiple low-risk basal cell carcinomas in sporadic or basal cell naevus syndrome patients.
New drug for moderate to severe hidradenitis suppurativa
A clinical trial to assess the safety and effectiveness of a new drug for hidradenitis suppurativa.
New potential treatment for adult males with Tourette Syndrome
A study to evaluate the safety and efficacy of new drug in male patients aged 18 to 50 with Tourette Syndrome (TS).
New treatment for young people with depression
SKY-D is investigating whether ketamine is an effective treatment for young people with depression.
Novel blood collection device to help resource-poor countries with diagnostic testing
Seeking VIDS patients who are living with hepatitis B, hepatitis C or HIV to provide blood samples for the development of a new diagnostic test sampling and storage device for resource-poor countries.
Novel treatment for non-alcoholic fatty liver disease
A trial to test the effectiveness of a novel non-invasive treatment for fatty liver disease.
OPT-302 with ranibizumab for neovascular age-related macular degeneration
The ShORe trial aims to determine if the investigational medication OPT-302 will improve vision for people with wet age-related macular degeneration (AMD) when given in combination with ranibizumab, compared to ranibizumab alone.
Perampanel to control and prevent seizures in patients with brain tumours
A randomised controlled trial assessing the safety and effectiveness of perampanel, an anti-epileptic drug, in people with brain tumours.
Possible new drug for Crohn’s disease
We are looking for people with Crohn's disease to participate in a study to determine the safety and effectiveness of a new study medication, guselkumab.
Possible treatment for Parkinson’s disease
Cerevel Therapeutics has begun a study of an experimental drug called CVL-751 as a possible treatment for people with Parkinson’s disease.
PRAX-944 as a potential treatment for essential tremor
A clinical trial evaluating the efficacy, safety, tolerability, and pharmacokinetics of PRAX-944 in adults with essential tremor.
Remibrutinib for chronic spontaneous urticaria
A clinical trial to assess a new drug for chronic spontaneous urticaria (CSU) not controlled with antihistamine medication or omalizumab (Xolair®) in the past.
Sailuotong for vascular dementia or Alzheimer’s disease with cerebrovascular disease
A clinical study that is testing a new herbal medicine formula treatment for vascular dementia or Alzheimer’s disease with cerebrovascular disease.
Seladelpar as a treatment for primary biliary cholangitis (PBC)
A study to evaluate the safety and effectiveness of an investigational drug, seladelpar, in treating patients with primary biliary cholangitis (PBC).
Sodium selenate for probable behavioural variant frontotemporal dementia
A trial to test sodium selenate as a disease-modifying treatment for probable behavioural variant frontotemporal dementia (bvFTD).
Spesolimab for the treatment of generalised pustular psoriasis
A study to test whether spesolimab prevents flare-ups in patients with generalised pustular psoriasis.
Spesolimab for the treatment of hidradenitis suppurativa
A study to measure how safe and effective spesolimab (the study drug) is in treating participants with moderate to severe hidradenitis suppurativa (HS).
Study to understand risk of Alzheimer’s disease in middle-aged adults
An Australian-first online study of psychological, lifestyle and genetic factors that increase risk of Alzheimer’s disease.
Survey for carers of individuals with mental illness
A survey to better understand the experiences of caregivers and siblings of people who have experienced a manic episode or psychosis.
Swabs required for research to develop point-of-care testing for infectious diseases
ZiP Diagnostics requires human samples for research into developing point-of-care (PoC) diagnostic tests for a range of infectious diseases.
Tirzepatide for people with type 2 diabetes
A clinical trial investigating the safety and effectiveness of tirzepatide taken once weekly compared to insulin taken once daily in people with type 2 diabetes and increased cardiovascular risk.
Treatment for moderately to severely active ulcerative colitis
A clinical trial to assess whether guselkumab and golimumab when used together is safe and effective for treating participants with moderately to severely active ulcerative colitis (UC).
Understanding antigen triggers in psoriasis
A non-interventional study to investigate triggers in psoriasis.