Clinical trials are a very important part of the research process. New treatments, medications and medical devices cannot be approved for use in Australia without going through clinical trials. Find out more about clinical trials.

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73 results found

Glucose control with next generation insulin pump system in adults with diabetes

A clinical trial to improve glucose control with a next generation insulin pump system in adults with diabetes and advanced kidney disease

Currently recruiting

KBL697 for the treatment of ulcerative colitis

Study investigated Lactobacillus gasseri in patients with mild to moderate active ulcerative colitis.

Study completed — 1

KPL-716 to reduce pruritus in people with prurigo nodularis

A clinical trial to assess a new drug (KPL-716) for prurigo nodularis (PN).

Study in progress

Ligelizumab for chronic spontaneous urticaria

A clinical trial to assess a new drug called ligelizumab for the treatment of chronic spontaneous urticaria (CSU).

Study in progress

Mirikizumab for moderate to severely active Crohn’s disease

A clinical trial to assess the safety and effectiveness of a new drug, mirikizumab, for moderate to severely active Crohn’s disease.

Study in progress

Mirikizumabin for moderately to severely active ulcerative colitis

A clinical trial to assess the safety and effectiveness of a new drug, mirikizumab, in conventional-failed and biologic-failed patients with moderately to severely active ulcerative colitis (UC).

Study in progress

mRNA vaccine for preventing cytomegalovirus infection

A clinical trial seeking to develop an mRNA vaccine for preventing cytomegalovirus (CMV) infection.

Study in progress

Nemolizumab for the treatment of moderate to severe atopic dermatitis

A clinical trial to assess safety and effectiveness of a new drug for eczema called nemolizumab.

Study in progress

Neural mechanisms of ketamine antidepressant treatment

The NeuroKet study aims to understand how ketamine works as an antidepressant medication. To find out, we are looking at brain activity using Magnetic Resonance Imaging (MRI) scans.

Currently recruiting

New add-on therapy to infliximab for ulcerative colitis

A clinical trial to assess the effectiveness of a new add-on therapy (PF-06687234) to infliximab.

Study completed — 2021

New blood test to detect bowel cancer

Seeking adults diagnosed with bowel cancer who will be having surgery, chemotherapy or radiation therapy in the next 30 days for a study to assess the effectiveness of a new blood test to detect bowel cancer.

Study in progress

New blood test to diagnose and monitor autoimmune blistering skin conditions

A prospective study on serum antibodies against target antigens of bullous autoimmune diseases and genetic susceptibility.

Currently recruiting

New drug for basal cell carcinoma

A study to assess the safety and efficacy of ASN-002 combined with a hedgehog pathway inhibitor (vismodegib) in the treatment of multiple low-risk basal cell carcinomas in sporadic or basal cell naevus syndrome patients.

Study is ongoing

New drug for moderate to severe hidradenitis suppurativa

A clinical trial to assess the safety and effectiveness of a new drug for hidradenitis suppurativa.

Study in progress

New potential treatment for adult males with Tourette Syndrome

A study to evaluate the safety and efficacy of new drug in male patients aged 18 to 50 with Tourette Syndrome (TS).

Study in progress

New treatment for moderate-to-severe plaque psoriasis

Treatments that are highly selective in inhibiting the body's immune response have the potential to increase quality of life for people with plaque psoriasis.

Currently recruiting

New treatment for young people with depression

SKY-D is investigating whether ketamine is an effective treatment for young people with depression.

Study completed

Novel blood collection device to help resource-poor countries with diagnostic testing

Seeking VIDS patients who are living with hepatitis B, hepatitis C or HIV to provide blood samples for the development of a new diagnostic test sampling and storage device for resource-poor countries.

Study in progress

Novel treatment for non-alcoholic fatty liver disease

A trial to test the effectiveness of a novel non-invasive treatment for fatty liver disease.

Currently recruiting

OPT-302 with ranibizumab for neovascular age-related macular degeneration

The ShORe trial aims to determine if the investigational medication OPT-302 will improve vision for people with wet age-related macular degeneration (AMD) when given in combination with ranibizumab, compared to ranibizumab alone.

Currently recruiting

Perampanel to control and prevent seizures in patients with brain tumours

A randomised controlled trial assessing the safety and effectiveness of perampanel, an anti-epileptic drug, in people with brain tumours.

Study in progress

Possible new drug for Crohn’s disease

We aimed to determine the safety and effectiveness of a new study medication, guselkumab, for people with Crohn's disease

Study in progress

Possible treatment for Parkinson’s disease

Cerevel Therapeutics has begun a study of an experimental drug called CVL-751 as a possible treatment for people with Parkinson’s disease. 

Currently recruiting

PRAX-944 as a potential treatment for essential tremor

A clinical trial evaluating the efficacy, safety, tolerability, and pharmacokinetics of PRAX-944 in adults with essential tremor.

Study in progress

Psychedelic-assisted therapy for depression

This large international trial will examine the efficacy and safety of a new psychedelic-assisted therapy for treatment-resistant depression.

Currently recruiting

Remibrutinib for chronic spontaneous urticaria

A clinical trial to assess a new drug for chronic spontaneous urticaria (CSU) not controlled with antihistamine medication or omalizumab (Xolair®) in the past.

Study in progress

Ritlecitinib in adults with non-segmental vitiligo

This trial is investigating a medication for treating people living with non-segmental vitiligo.

Currently recruiting

Sailuotong for vascular dementia or Alzheimer’s disease with cerebrovascular disease

A clinical study that is testing a new herbal medicine formula treatment for vascular dementia or Alzheimer’s disease with cerebrovascular disease.

Currently recruiting

Seladelpar as a treatment for primary biliary cholangitis (PBC)

A study to evaluate the safety and effectiveness of an investigational drug, seladelpar, in treating patients with primary biliary cholangitis (PBC).

Study in progress

Simufilam for people with mild to moderate Alzheimer’s dementia

A clinical trial to assess the efficacy of Simufilam in mild to moderate Alzheimer’s dementia

Currently recruiting