The Royal Melbourne Hospital Department of Diabetes and Endocrinology is strongly committed to improvement through research and innovation. We have shown that ongoing research and quality initiatives lead to tangible improvements in clinical outcomes.

About our research

Our clinical and laboratory research activities integrate basic, translational and health delivery clinical research with clinical services and education of patients.

Through this commitment we have developed an infrastructure and support mechanisms for early career and established investigators.

Our clinical and laboratory research activities integrate basic, translational and health delivery clinical research with clinical services and education of patients.

A strength of our research program is that we are able to integrate basic science, translational science, and clinical trials to achieve improved health outcomes for patients with endocrine disease.

Our focus

We are committed to our research program in the three major endocrine pillars of diabetes, bone mineral and pituitary disorders. Specific areas of interest include:

  • Prevention, prediction and treatment of type 1 diabetes
  • Medical device technologies with insulin pumps and glucose sensors
  • Precision diagnostics and therapeutics for type 2 diabetes and other forms of diabetes
  • Diabetes complications
  • Inpatient diabetes care
  • Bone and mineral disorders, including osteoporosis
  • Pituitary disorders

Current research studies

We are currently undertaking research studies for:

  • Stoic-D Type 1
  • ForeSight
  • alphaMSH
  • TrialNet

Find out more about current clinical trials.

Our achievements

  • Extensive type 1 diabetes autoimmunity screening programs
  • Largest cluster-randomised trial in the world of hospital diabetes in non-critical care
  • Design of peripheral quantitative CT and data analysis to become a valuable tool in the evaluation of bone fragility


A storm off the charts: a case of thyroid storm due to thyrotoxicosis factitia

Giang, NA; Lafontaine, N; Kyi, M

(2021), Intern. Med. J., 806-807

DOI: 10.1111/imj.15323

Advances in Type 1 Diabetes Prediction Using Islet Autoantibodies: Beyond a Simple Count

So, M; Speake, C; Steck, AK; Lundgren, M; Colman, PG; Palmer, JP; Herold, KC; Greenbaum, CJ

(2021), Endocr. Rev., 584-604

DOI: 10.1210/endrev/bnab013

Approach to Interpreting Common Laboratory Pathology Tests in Transgender Individuals

Cheung, AS; Lim, HY; Cook, T; Zwickl, S; Ginger, A; Chiang, C; Zajac, JD

(2021), J. Clin. Endocrinol. Metab., 893-901

DOI: 10.1210/clinem/dgaa546

Latest news & events

Trial helping provide better care for diabetes patients in hospital
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T1D blood spot test trial
World first at-home test for diabetes proven to work
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John Wentworth T1D
Common drug could help slow Type 1 diabetes
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Doctor checking child's blood sugar
Launch of Australian-first trial for young people with type 1 diabetes
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A/Prof John Wentworth with child and mother from type 1 diabetes study
At-home screening shown to help prevent serious illness from type 1 diabetes
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The RMH Parkville entrance
The RMH partners with Australian Centre for Accelerating Diabetes Innovations
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Close up of blood sugar test
The RMH researchers receive $1.8 million in funding for diabetes trial
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Finger prick procedure
New research improves screening efficiency for type 1 diabetes
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Contact us
Diabetes Clinical Research Unit
(03) 9342 7278
Test tube used for research
Donate now

Diabetes is the epidemic of this century and the biggest challenge confronting the Australian health system. We conduct research for diabetes type 1, diabetes type 2 and endocrine disorders.

If you'd like to support our research work, donate now.

Diabetes and Endocrinology research nurse with patient in Clinical Trials Centre
About clinical trials

We need clinical trials to prove that new treatments are safe and effective for people to use. They are essential to the discovery of new medications and devices, neither of which can be approved for use in Australia without clinical trials.

Last updated 09 February 2023