A pre-screening study to find eligible participants for future clinical trials that test new drugs for Alzheimer’s disease.
About this study
The purpose of this pre-screening study is to identify people that may be good candidates for participation in screening for Alzheimer’s disease studies where an experimental medication (i.e. a medication that is not approved by the Therapeutic Goods Administration (TGA)) will be investigated to see if it is an effective and safe treatment for Alzheimer’s disease.
Anticipated closure of enrolment: 2035
Who can take part
You may be eligible to participate if you:
- are between the ages of 50 to 90 years (adult, older adult)
- report of objective or subjective memory concerns (by the participant and/or their informant) within the last year with or without a previous clinical diagnosis of mild cognitive impairment or dementia due to alzheimer’s disease
You may not be eligible to participate if you:
- require dependency in basic activities of daily living due to cognitive impairment
- have visual or auditory impairment that would prevent you from performing the cognitive assessments (eyeglasses and hearing aids are permitted)
- have any self-reported evidence or known diagnosis of a neurological or neurodegenerative condition that may lead to cognitive impairment other than alzheimer’s disease
- have a history of severe, clinically significant central nervous system trauma
- have any serious medical condition that precludes safe participation and completion of a clinical study
What's involved for you
If you agree to take part, the study will last for approximately 2 weeks and will involve:
- filling out questionnaires with information about yourself such as age, sex, years of education, occupation, and medical history
- performing a short term memory test
- collection of a blood sample
Ethics
All research in Australia involving human participants is reviewed by an independent group called a Human Research Ethics Committee (HREC). The ethical aspects of this research study have been approved by an Australian registered and certified HREC.
This study is being carried out according to the National Statement on Ethical Conduct in Human Research (2025). This statement protects the interests of people who agree to participate in human research studies.